Chapter 2 - The Iso Effect

Mission 1 - In the Family
Unlock Requirements: Recruit 4 Heroes Complete 1 Star Mastery in Acquire a total of 7 Story Mastery Stars

Location: Little Italy

Team-Up: She-Hulk Battles= Low: x2

Medium: x3

High: x2

Mini-Boss= Minimum Cleared: 4

Team-Up: She-Hulk (Optional)

Boss= Minimum Cleared: 5

Team-Up: She-Hulk

Boss Drops: Knuckle Sting, Batstone 2.357 Minigun

Challenge Mode Boss Drop: Custom Frank Castle Special

Deploys=

Mission 2 - The Sound of Feathers Ruffling
Unlock Requirements: Own an Upgraded Jet Complete 1 Star Mastery in Chapter 2 - Mission 1

Location: Bellevue Hospital

Team-Up: Spider-Man Battles=

Mini-Boss= Minimum Cleared: 3

Team-Up: Spider-Man

Boss= Minimum Cleared: 5

Team-Up: Spider-Man

Boss Drops: Pyro-Tonfa, Third Law Nullifier

Challenge Mode Boss Drop: Custom M616 Combat Shotgun

Deploys=

Mission 3 - Step into the Shadows
Unlock Requirements: Complete 1 Star Mastery in Chapter 2 - Mission 2

Location: Hell's Kitchen

Team-Up: Daredevil Battles=

Mini-Boss= Minimum Cleared: 4

Team-Up: Daredevil

Boss= Minimum Cleared: 5

Team-Up: Daredevil

Boss Drops: Chain Blade, Assault Shotgun

Challenge Mode Boss Drop: Custom Revolt

Deploys=

Epic Boss= Must finish ALL battles and deploys before the Epic Boss will appear

Team-Up: Daredevil

Epic Boss Drops: Grecian Sai, D.A.R.S. Suppressor

Challenge Mode Epic Boss Drop: Custom Grecian Sai

Mission 4 - Mean People
Unlock Requirements: Complete 1 Star Mastery in Chapter 2 - Mission 3

Location: Pier 94

Team-Up: Iron Fist Battles=

Mini-Boss= Minimum Cleared: None

Team-Up: Iron Fist

Boss= Minimum Cleared: 5

Team-Up: Iron Fist

Boss Drops: Tidal Fist, S.A. "Ambush"

Challenge Mode Boss Drops: Custom Bolt-Action 4 Bore

Deploys=

Mission 5 - Mutate or Die
Unlock Requirements: Complete 1 Star Mastery in Chapter 2 - Mission 4

Location: Yorkville

Team-Up: Phoenix Battles=

Mini-Bosses= Team-Up: Phoenix

Boss= Minimum Cleared: 8

Team-Up: Phoenix

Boss Drops: Batstone 2.357 Minigun, Offensive Accelerator

Challenge Mode Boss Drop: Custom Pyro Technique

Deploys=

Premium Mission: Ulterior Motive
Location: Avengers Mansion

Team-Up: Iron Man

Note: Mission difficulty scales to players' agent level Battles=

Heroic Battle= Minimum Cleared: 4

Need: Fandral

Team-up: Volstagg, Hogun

Potential Gear Reward: Random Deploy Gear, Disciplined Empowered Iso-8, Loquacious Empowered Iso-8, Voracious Empowered Iso-8

Mini-Bosses= Team-Up: None

Boss= Minimum Cleared:  7

Team-Up:  Iron Man

Boss Drops: EMP Blaster, Uni-Pulse

Challenge Mode Boss Drops: EMP Blaster, Custom Eagle's Eye

Deploys=